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The neurotransmitter GABA is present around the central canal and is known to affect cells within other postnatal neurogenic niches

The neurotransmitter GABA is present around the central canal and is known to affect cells within other postnatal neurogenic niches. depolarised all ependymal cells tested; the partial antagonism of this response by bicuculline and gabazine indicates that GABAA receptors contribute to this response. A lack of effect by baclofen suggests that GABAB receptors do not contribute to the GABAergic response. The ability of ependymal cells to respond to GABA suggests that GABA Alvimopan (ADL 8-2698) could be capable of influencing the proliferation and differentiation of cells within the neurogenic niche of the postnatal spinal cord. (2, 6)?=?0.310, (3)?=?3.685, (2, 4)?=?2.601,…
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