17
Dec
To assess this concern, 1.9 billion anti-CTXII particles (460 antibody molecules per particle) in 30 L of Buffer 1 were mixed with 300 L of either hyaluronidase-treated or native bovine synovial fluid, incubated with gentle mixing for 1 h, then divided into 25 L samples of approximately 150 million particles per sample. knee OA. CTXII could be magnetically captured from a MK-6913 rodent stifle without the need to aspirate fluid and showed 10 fold changes in CTXII levels from OA-affected bones relative to contralateral control bones. Combined, these data demonstrate the ability and level of sensitivity of magnetic capture for…