Glutamate (Metabotropic) Group I Receptors

Our recent experiments have revealed a new exon, 1g, regulated from the promoter of exon 1a

Our recent experiments have revealed a new exon, 1g, regulated from the promoter of exon 1a. at early stages of their differentiation ATRA, but not 1,25D, upregulates the expression of expression in response to ATRA, depending on the AML cell line examined [12,13]. Since beneficial effects of 1,25D and ATRA combination treatment in anticancer therapy have been reported and their wider use postulated [14], the effects of such combination towards normal cells should be addressed. Hematopoiesis seems to be the most relevant process which might be influenced by ATRA and 1,25D. The roles of vitamin A and its most active…
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