19
Jul
They have also been proposed to play a role in viral persistence by acting as virus reservoirs since they are long-lived cells that are resistant to virus-induced cytotoxicity, cell host restriction, CD8+ T lymphocyte-mediated killing, and some antiretroviral therapies [68C73]. Heterotypic fusion Myeloid cells are able to fuse with poorly fusion competent cells. mediating the early stages of fusion, focusing on cell-surface receptors involved in the cell-to-cell adhesion steps that ultimately lead to multinucleation. Given that cell-to-cell fusion is a complex and well-coordinated process, we will also describe what is currently known about the evolution of F-actin-based structures involved in…