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Jan
Nucleotidase and alkaline phosphodiesterase We activities were considered as markers for the plasma membrane portion and showed an approximately 45-fold enrichment compared to the whole homogenate. membrane is an early event of the apoptotic cellular program that may represent an trigger for the generation of aCL. Keywords: cardiolipin, apoptosis, anticardiolipin antibodies, COH000 antiphospholipid antibody syndrome Introduction Programmed cell death (PCD) or apoptosis, a common phenomenon that issues any nucleated cell type, is usually a cardinal element of immune system homeostasis [1,2]. Apoptosis may be defined morphologically and biochemically [3]. In most cases, PCD is accompanied by characteristic ultrastructural alterations (cell…